Here are the possible solutions for any one of man's best friends clue
Answer
Clue
Relevancy
dog
Clue
Any one of man's best friends
Definition
to follow closely behind
gigli
Clue
2003 bomb imdb.com described as "The violent story about how a criminal lesbian, a tough-guy hit-man with a heart of gold, and a mentally challenged man came to be best friends through a hostage"