Here are the possible solutions for big first for junior clue
Answer
Clue
Relevancy
grandson
Clue
Junior's junior
Junior's junior, to senior
Definition
the son of one's son or daughter
iii
Clue
Junior's junior
soph
Clue
Junior's junior, briefly
tre
Clue
Nickname for a junior's junior
step
Clue
Big first for Junior
acne
Clue
Condition that may first appear in junior high
Definition
a skin disease caused by inflammation of the sebaceous follicles, esp. on the face, neck, and shoulders
fun
Clue
First word across in the first-ever crossword (1913) and the first of a dozen appearances of the word in this puzzle's grid, written word search-style (left, right, down, and diagonally) ... Can you f