Crossword puzzle clue "big headache"

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Here are the possible solutions for big headache clue

Answer
Clue
Relevancy
hassle
Clue
Big headache
Definition
to harass
prnightmare
Clue
Big headache for a company rep
acne
Clue
Teen headache
High schooler's headache
Definition
a skin disease caused by inflammation of the sebaceous follicles, esp. on the face, neck, and shoulders
advil
Clue
Headache relief brand
ail
Clue
Have a headache
Definition
to be indisposed
aleveinthelurch
Clue
Headache medicine administered to a creepy butler?
algae
Clue
Pool owner's headache
Definition
ALGA, (Latin) a seaweed

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