Here are the possible solutions for goes up in smoke clue
Answer
Clue
Relevancy
stogie
Clue
Smoke in a smoke-filled room, perhaps
burns
Clue
Goes up in smoke
Definition
BURN, to destroy by fire
ganjapreneur
Clue
Businessman whose money goes up in smoke?
lab
Clue
Smoke-filled room, if the chemistry experiment goes awry
Definition
(short for) a laboratory
tobacco
Clue
It goes up in smoke
asfaras
Clue
What goes before that goes?
ernest
Clue
Recurring movie character who "Goes to Jail," "Goes to Camp," and "Saves Christmas"
madea
Clue
Title character of film who has a family reunion and class reunion, goes to jail, has a big happy family, goes into the Witness Protection Program, and celebrates Christmas
