Crossword puzzle clue "irritate big time"

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Here are the possible solutions for irritate big time clue

Answer
Clue
Relevancy
gall
Clue
Irritate big-time
Definition
to make sore by rubbing
abrade
Clue
Irritate
Irritate by rubbing
Definition
to wear away by friction
acerbate
Clue
Irritate
Definition
to embitter, to irritate
againstthegrain
Clue
Go ___ (irritate)
anger
Clue
Irritate
Definition
wrath
annoy
Clue
Irritate
Definition
to be troublesome to
bother
Clue
Irritate
Definition
to annoy

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