Crossword puzzle clue "issue opener"

Here are the possible solutions for issue opener clue

Answer
Clue
Relevancy
non
Clue
Issue opener?
Definition
(Latin) not
abel
Clue
Second issue?
abner
Clue
Groom on the cover of Life's 3/31/52 issue
academicfreedom
Clue
Burning issue in the U. S. A.
acne
Clue
Sebaceous gland issue
Facial issue for many teenagers
Adolescent's issue
Definition
a skin disease caused by inflammation of the sebaceous follicles, esp. on the face, neck, and shoulders
activist
Clue
Issue-oriented person
Definition
an advocate of activism

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