Crossword puzzle clue "it's a big pain"

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Here are the possible solutions for it's a big pain clue

Answer
Clue
Relevancy
agony
Clue
It's a big pain
Definition
extreme suffering
aleve
Clue
Big name in pain relief
earache
Clue
Big pain for an elephant?
Definition
a pain in the ear
headache
Clue
Big pain
Definition
a pain inside the head
motrin
Clue
Big name in pain relief
gazillion
Clue
Big, big, big number
Definition
an indefinitely large number, also KAZILLION
massive
Clue
Big, big, big
Definition
of great size
mega
Clue
Big, big, big: Prefix
Definition
very big

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