Crossword puzzle clue "it's a major pain"

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Here are the possible solutions for it's a major pain clue

Answer
Clue
Relevancy
agony
Clue
Major pain
It's a major pain
Definition
extreme suffering
hassle
Clue
Major pain
Major pain in the neck
Definition
to harass
pill
Clue
Major pain
Definition
to administer small, rounded balls of medicine
asharp
Clue
Note in B major but not E major
heller
Clue
Creator of Major Major
Definition
(Czech) a Czech monetary unit, also HALER
rank
Clue
Major or major general
Definition
disagreeable in odour or taste

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