Crossword puzzle clue "it starts the western hemisphere's most populous city"

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Here are the possible solutions for it starts the western hemisphere's most populous city clue

Answer
Clue
Relevancy
sao
Clue
It starts the Western Hemisphere's most populous city
___ Paulo (most populous city of the Southern Hemisphere)
saopaulo
Clue
Most populous Southern Hemisphere city
americas
Clue
Most of the Western Hemisphere (with "the")
Most of the Western Hemisphere, with "the"
opossums
Clue
Most prevalent Western Hemisphere marsupials
Definition
OPOSSUM, (Native American) any of various small or medium-sized marsupial mammals, mostly arboreal
sanjuan
Clue
Western Hemisphere city founded in 1521
ano
Clue
It starts and ends in inverno in the Northern Hemisphere

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