Crossword puzzle clue "major headache"

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Here are the possible solutions for major headache clue

Answer
Clue
Relevancy
hassle
Clue
Major headache
Definition
to harass
asharp
Clue
Note in B major but not E major
heller
Clue
Creator of Major Major
Definition
(Czech) a Czech monetary unit, also HALER
rank
Clue
Major or major general
Definition
disagreeable in odour or taste
snafu
Clue
Major's major mishap
acne
Clue
Teen headache
High schooler's headache
Definition
a skin disease caused by inflammation of the sebaceous follicles, esp. on the face, neck, and shoulders
advil
Clue
Headache relief brand

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