Crossword puzzle clue "makes it so that you can't try anymore"

Makes it so that you can't try anymore?

Drinking establishment I can't really go to anymore--autograph hounds, you know

"You can't boss me around anymore!"

"___ first you don't succeed, try, try again": 2 wds.

Org. for Ann Miller, who said "You try to help them, try to sing and dance ... it's heartbreaking."

The Rolling Stones' 'You Can Make -- You Try'

"Ladies and gentlemen! Step right up and try your hand at ___, a game where you punt a pail as far as you can!"

Can't take it anymore