Crossword puzzle clue "most essential part"

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Here are the possible solutions for most essential part clue

Answer
Clue
Relevancy
core
Clue
Most essential part
Most essential
Definition
to remove the central part of
heart
Clue
Most essential part
Definition
to hearten, encourage
heartandsoul
Clue
Most essential parts
inner
Clue
Essential — most private
Definition
interior
pith
Clue
Most essential element
Definition
to sever the central nervous system of
tetris
Clue
"The most-played, most-imitated, most influential puzzler of all time," per the video game website IGN
cog
Clue
Minor but essential part
Definition
to cheat at dice

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