Crossword puzzle clue "most hopeless"

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Here are the possible solutions for most hopeless clue

Answer
Clue
Relevancy
direst
Clue
Most hopeless
    Most hopeless
Definition
DIRE, disastrous
nadir
Clue
Most hopeless moment
Definition
(Arabic) the point of the heavens diametrically opposite to the zenith
tetris
Clue
"The most-played, most-imitated, most influential puzzler of all time," per the video game website IGN
abject
Clue
Utterly hopeless
Hopeless
Definition
humble; miserable; craven
agnew
Clue
"Hopeless, hysterical hypochondriacs of history" speaker
allup
Clue
Hopeless

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