most significant | Crossword Clue

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Here are the possible solutions for most significant clue

Answer

Clue

Relevancy

greatest

Clue

Most significant

Definition

the greatest person in some field

main

Clue

Most significant

Definition

chief, principal

mainclaimtofame

Clue

Most significant entitlement

tetris

Clue

"The most-played, most-imitated, most influential puzzler of all time," per the video game website IGN

adam

Clue

Eve's significant other

agony

Clue

Significant suffering

Definition

extreme suffering

ahem

Clue

Significant cough.

Definition

a sound expressing delicate interruption

alone

Clue

Forever ___ (meme for people who will *never* have a significant other as long as they live)

Definition

solitary, apart from others

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