Crossword puzzle clue "real pain"

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Here are the possible solutions for real pain clue

Answer
Clue
Relevancy
sham
Clue
Fall Out Boy "Champagne for My Real Friends, Real Pain for My ___ Friends"
"Champagne for my real friends, real pain for my ___ friends": Tom Waits
hassle
Clue
Real pain in the ass
Definition
to harass
pest
Clue
Real pain
Definition
an annoying person or thing
saddlesore
Clue
Real pain in the butt?
eyes
Clue
"Real ___, realize, real lies..." (Tupac lyric)
Definition
EYE, to watch closely
aboat
Clue
"I'm On ___" (2009 song by The Lonely Island featuring T-Pain)
acclimate
Clue
Harden against PAin, etc.
Definition
(US) to habituate to a climate not native, also ACCLIMATIZE

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