set off in a big way | Crossword Clue

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Answer

Clue

Relevancy

detonate

Clue

Set off, in a big way

Definition

to cause to explode

alarm

Clue

It may be set or set off

Definition

to strike with fear

longgone

Clue

Extinct since way back when ... and, in a way, what each set of circles represents

alienate

Clue

Turn off, in a big way

Definition

to make indifferent or unfriendly

gazillion

Clue

Big, big, big number

Definition

an indefinitely large number, also KAZILLION

massive

Clue

Big, big, big

Definition

of great size

mega

Clue

Big, big, big: Prefix

Definition

very big

ncaa

Clue

Org. for the Big East, Big South and Big 12

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