Here are the possible solutions for spam header targeted toward men and a hint to this week's theme clue
Answer
Clue
Relevancy
addmoreinches
Clue
Spam header targeted toward men, and a hint to this week's theme
clue
Clue
Hint (and a hint to this puzzle's theme)
Definition
to obtain guiding information
tgif
Clue
End-of-week cry ... or a hint to the puzzle theme
axe
Clue
Grooming product brand targeted at young men
Definition
to chop or cut down, also AX
asif
Clue
Valley girl's "yeah, right" [IMPORTANT: SEE THE 'NOTE' (above) for key info about this week's puzzle and SEE THE LAST CLUE DOWN for the explanation of last week's puzzle.]
bleed
Clue
Run in the wash[To fully understand this week's and last week's puzzles, SEE NOTE ABOVE]
Definition
to lose blood
dayafterday
Clue
Week in and week out
alphanumerics
Clue
Certain character set ... and a hint to translating this week's final answer
