Crossword puzzle clue "true pain"

Here are the possible solutions for true pain clue

Answer
Clue
Relevancy
agony
Clue
True pain
Definition
extreme suffering
tuggspeedman
Clue
Oscar-winning star of "Tropic Blunder: The True Story Behind the Making of the Most Expensive Fake True War Story Ever" in 2008's "Tropic Thunder"
aboat
Clue
"I'm On ___" (2009 song by The Lonely Island featuring T-Pain)
acclimate
Clue
Harden against PAin, etc.
Definition
(US) to habituate to a climate not native, also ACCLIMATIZE
acetaminophen
Clue
Pain reliever and fever reducer
Definition
(US) paracetamol, a chemical compound used in medicine to relieve pain and fever
ache
Clue
Pain
Pain in the neck
Dull pain
Definition
to endure a dull lasting pain, also AKE

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